Vkh Syndrome Symptoms

The most common symptoms include headaches inflammation of all layers of the colored part of the eye panuveitis white patches of skin vitiligo hair loss alopecia dizziness and nausea inner ear related problems and vision and hearing loss.

Vkh syndrome symptoms. Meningitis csf pleocytosis cranial nerve palsies hemiparesis transverse myelitis and ciliary. Vogt koyanagi harada syndrome vkh is a multisystem disease that presents with a combination of ophthalmological neurological and dermatological signs and symptoms. Clouding of the lens cataracts build up of pressure in the eyes glaucoma abnormal blood vessels growth under the retina choroidal neovascularization. Vogt koyanagi harada syndrome vkh disease is an autoimmune disease that affects people of asian hispanic middle eastern and native american descent.

Melanocytes are the skin cells that produce the pigment melanin. The eye symptoms may be accompanied by a varying constellation of systemic symptoms such as auditory tinnitus vertigo and hypoacusis neurological meningismus with malaise fever headache nausea abdominal pain stiffness of the neck and back or a combination of these factors. Melanin is the substance that gives pigment color to our skin hair and eyes. In this phase symptoms such as generalized muscle weakness headache loss of muscle use on.

The most noticeable symptom is a rapid loss of vision. The disease is characterised by bilateral diffuse uveitis with pain redness and blurring of vision. Loss of hearing and loss of hair alopecia and skin color may occur along with whitening loss of pigmentation of the hair and eyelashes poliosis. There may also be neurological signs such as severe headache vertigo nausea and drowsiness.

Initially there are headaches meningismus csf pleocytosis and occasionally focal neurologic signs. In the ophthalmic auditory phase symptoms such as blurry vision pain and eye irritation. Vogt koyanagi syndrome characterized by chronic severe anterior uveitis alopecia poliosis cutaneous as well as perilimbal vitiligo also known as sugiura s sign and dysacusia. Vkh syndrome has varying clinical manifestations depending on the stage of the disease.

Vkh disease attacks the melanocytes in the body. The main defining clinical finding of vkh is severe bilateral granulomatous panuveitis inflammation throughout the uveal tract in the eye.